I did not find a solution for this in other discussions; maybe this will help others who get this problem.
After my first print where I accidentally used Slic3r (with no Vertex optimized configs), I found that the CuraEngine output caused the printer to display “190/0 0/50” and at the bottom “Heating Bed”, and the print never started (the 190 decreases as it cools after loading filament into the extruder). Now I know there is no heated bed, so why this display and why a 0 setpoint for extruder 1? It took me hours to track down, including re-flashing the Vertex Arduino code and re-installing the Vertex Repetier program with no change. It turns out that the CuraEngine slicer generates a bad G-Code statement in the start portion of the code. On line 8 it shows “M190 S50” which means ‘wait for the bed to reach 50 degrees’. When I comment out this line (by putting a ; in front), it works as expected.
In generating the G-Code, CuraEngine uses the statement “(IF_BED)M190 S(BED)” [you can see this in the CuraEngine Configuration]. It looks OK, but somehow the IF_BED is interpreted as True even though it is False. I’m sure when I remove this entire line from the Configuration I won’t have to comment out each G-Code before pressing Print, but I have no idea how to fix the initial problem. For a first-time user this was very distressing, but now I am very happy with the Vertex.