The best result is obtained when coating the bed with a 3D adhesive like Dimafix or 3D Lac.
Heat the bed to 90-100°. No brim needed (or only if the surface in contact with the bed is very small ).
Extruder temperature about 220°-225°.
I’ve closing with tape maximum of the vertex opened areas.
As there is a working abiant temp 30~35°c (vs 15~20°c before) and that solve 100% of the problem.
(Bed temp 80° extruder 225°c)